Why weed (and other cannabinoids) gives us—I mean, you—the munchies (arstechnica.com)

The regulation of appetite by the nervous system is a hot area of research due to the raging obesity/diabetes epidemic. An international team of researchers interested in the subject—none of whom hail from either Colorado or Amsterdam—astutely noticed that "the phenomenon of cannabis-triggered feeding in a state of satiety is a hallmark of marijuana use in humans." So they injected cannabinoids into sated mice to see how the drugs affected neurons in the hypothalamus known to regulate satiety, the feeling of fullness. They figured that the cannabinoids would decrease the activity of these neurons. They figured totally wrong.
http://arstechnica.com/science/2015/02/why-weed-and-other-cannabinoids-gives-us-i-mean-you-the-munchies/, 22.2.2015